Teacher’s Handbook "Entrepreneurship in the Classroom" is intended for teachers without entrepreneurial competences interested in introducing cross-curricular entrepreneurship topics in everyday teaching. The Handbook was created by teachers working on the Erasmus + project Start your own business. The project is aimed at developing entrepreneurial skills and encouraging self-employment of students of different profiles interests and competences. The intention of partner schools was to increase the quality of vocational education and training by introducing entrepreneurship as a cross-curricular topic or optional subject through this project. We believe that this will increase the students’ motivation for lifelong learning as well as for enrolling in vocational programs.